Rosiglitazone activation of PPARγ suppresses fractalkine signaling
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چکیده
منابع مشابه
Rosiglitazone activation of PPARγ suppresses fractalkine signaling
The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARgamma) is a key transcriptional regulator of both lipid metabolism and inflammation. The importance of PPARgamma is accentuated by the widespread use of synthetic PPARgamma agonists, thiazolidinediones (such as rosiglitazone), as drugs for insulin resistance and type II diabetes. Fractalkine (FKN) and FKN receptor (FR) p...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2009
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme-09-0090